This page provides links to resources and papers mentioned in my presentation of the recent modelling and research activities of Blue Brain.
Resources
Data and portals
https://portal.bluebrain.epfl.ch - The main data portal containing neuron and synapse models
https://bbp.epfl.ch/nmc-portal/downloads - Download the predicted rat local connectome
http://channelpedia.epfl.ch - Ion channel models and tons of data on ion channel kinetics
https://portal.bluebrain.epfl.ch/resources/models/mouse-projections/ - Predicted mouse connectome, comprising local and long-range connectivity
https://bbp.epfl.ch/nexus/cell-atlas - an atlas of the predicted whole-brain composition of adult mouse
https://reimann.science/2021/01/07/rat-somatosensory-cortex-connectivity/ - A neat visualization of our predicted rat connectome. Play around with it!
Code and programs
https://github.com/BlueBrain/BluePyOpt - General optimization framework. Used for building single cell electrical models
https://github.com/BlueBrain/insilico-vsdi - Used for calculating the VSDI signal from simulation results
https://github.com/BlueBrain/topological_sampling - Analysis code related to the Reimann et al., 2020 paper on spike coding. The raw data of that publication can be found at https://zenodo.org/record/4317336
https://github.com/MWolfR/targeting_specificity_test - A quick analysis showing the importance of statistical dependence when selecting synapses as a subset of potential synapses
Publications
Modelling / anatomy
Reconstruction and Simulation of Neocortical Microcircuitry - Cell, 2015
A Cell Atlas for the Mouse Brain - Frontiers in Neuroinformatics, 2018
Modelling / single-cell electrical
Reconstruction and Simulation of Neocortical Microcircuitry - Cell, 2015
Micro-connectomics
Reconstruction and Simulation of Neocortical Microcircuitry - Cell, 2015
Neuron Geometry Underlies Universal Network Features in Cortical Microcircuits - bioRxiv, 2020
A synaptic organizing principle for cortical neuronal groups - PNAS, 2011
Synaptic physiology
Simulation project: Voltage-sensitive dye imaging
Simulation project: Auditory surprise
Simulation project: Coding and its limitations
Cortical reliability amid noise and chaos - Nature Communications, 2019
Impact of higher order network structure on emergent cortical activity - Network Neuroscience, 2020
Simulation project: Plasticity
Simulation project: Neuromodulation